免疫分子与表观调控研究室研究成果

2017-06-23

近年发表主要文章:
1 Miaomiao Zhang, Qiaofei Liu, Siping Min,Xue Liang, Zhiqian Zhang, Xiaomin Su, Jinyi Liu, Yingying Chen, Mengmeng Wang, Yuan Zhang, Fenghua Guo, Zhujun Zhang and Rongcun Yang. Both MiR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid Derived Suppressor Cells by Modulating STAT3 Expression. The Journal of Immunology, 2011;186;4716-4724
2 Qiaofei Liu, Miaomiao Zhang, Xingran Jiang, Ziquan Zhang, Lingyun Dai, Siping Min, Xilong Wu, Qingsheng He, Jingyi Liu, Yuan Zhang, Zhujun Zhang and Rongcun Yang*,miR-223 suppresses differentiation of tumor-induced CD11b+Gr1+ myeloid derived suppressor cells from bone marrow cells International Journal of Cancer (On line)
3 Jing Z, Yuan X, Zhang J, Huang X, Zhang Z, Liu J, Zhang M, Oyang J, Zhang Y, Zhang Z, Yang R.. “Chromosome 1 Open Reading Frame 190 Promotes Activation of NF-kB Canonical Pathway and Resistance of Dendritic Cells to Tumor-Associated Inhibition In Vitro” J Immunol. 2010 Dec 1;185(11):6719-27. Epub 2010 Nov 3.
4 Zhuohan Zhang, Qiaofei Liu, Yongzhe Che, Bin Zeng, Guohui Jiao, Yinyan Yu, Zhizi Jing, Xin Yuan, Jiangbo Oyang, Yuan Zhang , Rongcun Yang, Antigen Presentation by dendritic cells in Tumors Is Disrupted by Altered Metabolism that Involves Pyruvate Kinase M2 and Its Interaction with SOCS3 . Cancer Research,2010,70(1):89-98. (IF, 8.2)
5 Zhuohan Zhang, Bin Zeng, Zhiqian Zhang,Yongzhe Che Yuan Zhang, Rongcun Yang. Suppressor of Cytokine Signaling 3 Promotes Bone Marrow Cells to Differentiate into CD8+T Lymphocytes in Lung Tissue via Up-regulating Notch1 Expression. Cancer Research, 2009, 69(4): 1578-86. (IF, 8.2)
6 Limin Chai, Lingyun Dai, Yongzhe Che, Jie Xu, Guojing Liu, Zhujun Zhang *,Rongcun Yang* . LRRC19, a novel member of the leucine-rich repeat protein family, activates NF-kB and induces expression of proinflammatory cytokines. BBRC 2009 388(3):543-8
7 Zhuohan Zhang, Bin Zeng, Guohui Jiao, Yuhao Li, Yu Liu, Yuan Zhang Rongcun Yang *. AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells .Clinical Immunology, 2009 ,3(3):324-32
8 Yu Liu , Yinyan Yu1, Suguang Yang, Bin Zeng1, Zhuohan Zhang1, Guohui Jiao, YuanZhang1,Limin Cai, Rongcun Yang1 . Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid derived suppressor cells. Cancer Immunology and immunotherapy, 2009, 58: 687-697
9 Yu Liu, Bin Zeng, Zhuohan Zhang, Yuan Zhang, Rongcun Yang. B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer. Clin Immunol. 2008, 129, 471-481
10 Bin Zeng, Haijie Li,Yu Liu,Zhuohan Zhang, Yuan Zhang, Rongcun Yang,. Tumor-induced Suppressors of Cytokine Signaling 3 Inhibits Toll-Like Receptor 3 Signaling in Dendritic Cell via Binding to Tyrosine Kinase 2. Cancer Research,2008, 68(13)5397-5404. (IF, 8.2)
11 Limin Chai, Lingyun Dai, Yongzhe Che, Jie Xu, Guojing Liu, Zhujun Zhang *,Rongcun Yang* . LRRC19, a novel member of the leucine-rich repeat protein family, activates NF-kB and induces expression of proinflammatory cytokines. BBRC 2009 388(3):543-8
12 李海洁,曾彬,张灼寒,王丽娜,张竹红,杨荣存. 小鼠免疫抑制蛋白SOCS3脯氨酸富集区为其生物学功能所必需. 中国生物化学和分子生物学报。2008,24(5)432-438
13 柴立民,车永哲,杨荣存。跨膜蛋白受体在LRRC19调节机体先天免疫应答反应中的作用,解放军医学杂志,2010;35(1)36-39
14 刘乔飞,杨荣存。微小RNA(microRNA)与免疫细胞分化及功能调节。中国免疫学杂志,2010,26(6)567-572
15 柴立民,张园,车永哲,杨荣存. LRRC19识别肿瘤坏死因子a等炎症因子参与肾脏的免疫应答,南开大学学报, 2011;44(1)60-65
专利 
1 发明专利:基于免疫耐受树突细胞筛选免疫耐受相关疾病的基因RGS1的方法。专利号:ZL2006 1 0013091.8
2 发明专利:筛选与鉴定治疗免疫耐受相关疾病功能基因SERPINH1的方法 专利号:ZL 2006 1 0013093.7
3 申请专利:细胞增殖相关基因CNKSR3与筛选方法及其应用 申请号:200810054129.5
4 申请专利:miR-223的新用途 申请号:200910244804.5
5 申请专利:微小RNA的新用途 申请号:201010294051.1