姓名：陈冬艳

职称：副研究员

一、教育经历

2003.9-2008.6 山东大学生命科学学院学院发育生物学专业，博士

二、工作经历

2014.1-今南开大学医学院，副研究员

2008.7-2013.12 南开大学医学院，讲师

三、研究方向（包括承担课题项目）

        1.  发育毒理学以及发育生物学

        2.  发作性睡病动物模型的构建及机理研究

    承担课题项目：

1.     学基金青年项目，利用可视可控hypocrite神经元凋亡的疾病模型进行发作性睡病发病机制研究，（项目编号：81901346，起止时间：2020/01-2022/12）

2.     科学手套箱微操作子系统研制，（起止时间： 2018/01-2019/12）

3.     应用基础与前沿技术研究计划，Rab23在斑马鱼神经发育中的功能研究，（项目编号：14JCQNJC09600，起止时间：2014/04-2017/03）

4.     校博士学科点专项科研基金，Rab23 在斑马鱼早期发育过程的功能研究，（项目编号：20100031120045，起止时间：2011/01-2013/12）

5.     科技计划项目, 10JCYBJC25300, G蛋白偶联雌激素受体对血管平滑肌细胞增殖作用和机理, （项目编号：10JCYBJC25300，起止时间：2010/10-2013/09）

四、学术兼职

        1.  中国神经生物学学会会员

        2.  天津市免疫学会会员

五、近5年发表论文

1.Tang YQ, Li ZR, Zhang SZ, Mi P, Chen DY, Feng XZ: Venlafaxine plus melatonin ameliorate reserpine-induced depression-like behavior in zebrafish. Neurotoxicology and teratology 2019, 76:106835.（共同通讯）

2.Mi P, Zhang QP, Zhang SH, Wang C, Zhang SZ, Fang YC, Gao JZ, Feng DF, Chen DY, Feng XZ: The effects of fluorene-9-bisphenol on female zebrafish (Danio rerio) reproductive and exploratory behaviors. Chemosphere 2019, 228:398-411.（共同通讯）

3.Mi P, Zhang QP, Li SB, Liu XY, Zhang SH, Li M, Chen DY, Zhao X, Feng DF, Feng XZ: Melatonin protects embryonic development and maintains sleep/wake behaviors from the deleterious effects of fluorene-9-bisphenol in zebrafish (Danio rerio). Journal of pineal research 2019, 66(1):e12530.（共同通讯）

4.Li X, Zhang Q, Peng X, Xu J, Zhang Y, Zhu J, Wang Y, An Y, Chen D: The effects of five types of tea solutions on epiboly process, neural and cardiovascular development, and locomotor capacity of zebrafish. Cell biology and toxicology 2019, 35(3):205-217.（通讯）

5.Zhang S, Liu X, Sun M, Zhang Q, Li T, Li X, Xu J, Zhao X, Chen D, Feng X: Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM). Behavioral and brain functions : BBF 2018, 14(1):13.（共同通讯）

6.Liu X, Zhang Q, Li S, Mi P, Chen D, Zhao X, Feng X: Developmental toxicity and neurotoxicity of synthetic organic insecticides in zebrafish (Danio rerio): A comparative study of deltamethrin, acephate, and thiamethoxam. Chemosphere 2018, 199:16-25.（共同通讯）

7.Zhang S, Xu J, Kuang X, Li S, Li X, Chen D, Zhao X, Feng X: Biological impacts of glyphosate on morphology, embryo biomechanics and larval behavior in zebrafish (Danio rerio). Chemosphere 2017, 181:270-280.（共同通讯）

8.Xu J, Zhang Q, Li X, Zhan S, Wang L, Chen D: The effects of copper oxide nanoparticles on dorsoventral patterning, convergent extension, and neural and cardiac development of zebrafish. Aquatic toxicology 2017, 188:130-137.（通讯）

9.Lin YH, Zhang W, Li JW, Zhang HW, Chen DY: [Amphioxus ortholog of ECSIT, an evolutionarily conserved adaptor in the Toll and BMP signaling pathways]. Molekuliarnaia biologiia 2017, 51(1):42-49.（共同通讯）

10.Li X, Zhang Y, Li X, Feng D, Zhang S, Zhao X, Chen D, Zhang Z, Feng X: Comparative analysis of biological effect of corannulene and graphene on developmental and sleep/wake profile of zebrafish larvae. Acta biomaterialia 2017, 55:271-282.（共同通讯）

11.Li X, Sun MZ, Li X, Zhang SH, Dai LT, Liu XY, Zhao X, Chen DY, Feng XZ: Impact of low-dose chronic exposure to Bisphenol A (BPA) on adult male zebrafish adaption to the environmental complexity: Disturbing the color preference patterns and reliving the anxiety behavior. Chemosphere 2017, 186:295-304.（共同通讯）

12.Li X, Sun D, Li X, Zhu D, Jia Z, Jiao J, Wang K, Kong D, Zhao X, Xu L, Zhao Q, Chen D, Feng X: PEGylation corannulene enhances response of stress through promoting neurogenesis. Biomaterials science 2017, 5(4):849-859.（共同通讯）

13.Li X, Ma J, Xu J, Zhu D, Li A, Che Y, Chen D, Feng X: Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. Neurochemical research 2017, 42(11):3268-3278.（共同通讯）

14.Li X, Liu XD, Li T, Li X, Feng DF, Kuang XY, Xu J, Zhao X, Sun MZ, Chen DY, Zhang ZX, Feng XZ: SiO2 nanoparticles cause depression and anxiety-like behavior in adult zebrafish. Rsc Adv 2017, 7(5):2953-2963.（共同通讯）

15.Li X, Guo JY, Li X, Zhou HJ, Zhang SH, Liu XD, Chen DY, Fang YC, Feng XZ: Behavioural effect of low-dose BPA on male zebrafish: Tuning of male mating competition and female mating preference during courtship process. Chemosphere 2017, 169:40-52.（共同通讯）

16.Li X, Li X, Chen D, Guo JL, Feng DF, Sun MZ, Lu Y, Chen DY, Zhao X, Feng XZ: Evaluating the biological impact of polyhydroxyalkanoates (PHAs) on developmental and exploratory profile of zebrafish larvae. Rsc Adv 2016, 6(43):37018-37030.（共同通讯）

17.Li X, Gao A, Wang Y, Chen M, Peng J, Yan H, Zhao X, Feng X, Chen D: Alcohol exposure leads to unrecoverable cardiovascular defects along with edema and motor function changes in developing zebrafish larvae. Biology open 2016, 5(8):1128-1133.（通讯）

18.Wang Y, Zhang Y, Li X, Sun M, Wei Z, Wang Y, Gao A, Chen D, Zhao X, Feng X: Exploring the Effects of Different Types of Surfactants on Zebrafish Embryos and Larvae. Scientific reports 2015, 5:10107.（共同通讯）

19.Li X, Li X, Li YX, Zhang Y, Chen D, Sun MZ, Zhao X, Chen DY, Feng XZ: The Difference between Anxiolytic and Anxiogenic Effects Induced by Acute and Chronic Alcohol Exposure and Changes in Associative Learning and Memory Based on Color Preference and the Cause of Parkinson-Like Behaviors in Zebrafish. Plos One 2015, 10(11).（共同通讯）

20.Li X, Liu B, Li XL, Li YX, Sun MZ, Chen DY, Zhao X, Feng XZ: SiO2 nanoparticles change colour preference and cause Parkinson's-like behaviour in zebrafish. Scientific reports 2014, 4:3810.（共同通讯）

六、讲授课程
 1. 胎学理论和实验（临床专业）
 2. 织胚胎学理论和实验（口腔专业）
 3. 组织胚胎学理论和实验（留学生）

七、联系方式
 1．通讯地址：天津市南开区卫津路94号
 2．电话：022-23502554
 3．E-mail：chendy@nankai.edu.cn