心血管药理实验室研究成果

2017-06-23

近年发表主要文章:
1. Y Wang, X Deng, Y Zhou, E Hendron, S Mancarella, MF Ritchie, X.D. Tang, Baba Y, T Kurosaki, Y Mori, J Soboloff, DL Gill. STIM protein coupling in the activation of Orai channels. Proc Natl Acad Sci USA. 2009.106(18): 7391-6
2. Ma, D., X. D. Tang, T.B. Rogers, and P.A. Welling, An Andersen-Tawil syndrome mutation in KIR2.1 (V302M) alters the G-loop cytoplasmic K+ conduction pathway. J Biol Chem, 2007. 282(8): 5781-9.
3. Soboloff, J., M.A. Spassova, X. D. Tang, T. Hewavitharana, W. Xu, and D.L. Gill, Orai1 and STIM reconstitute store-operated calcium channel function. J Biol Chem, 2006. 281(30): 20661-5.
4. X. D. Tang, M.L. Garcia, S.H. Heinemann, and T. Hoshi, Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing. Nature Struct Biol, 2004. 11(2): 171-8.
5. X. D. Tang, L.C. Santarelli, S.H. Heinemann, and T. Hoshi, Metabolic regulation of potassium channels (invited review). Annu Rev Physiol, 2004. 66: 131-59.
6. X. D. Tang, R. Xu, M.F. Reynolds, M.L. Garcia, S.H. Heinemann, and T. Hoshi, Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels. Nature, 2003. 425(6957): 531-5.
7. Ruan, H., X. D. Tang (co-first author), M.L. Chen, M.L. Joiner, G. Sun, N. Brot, H. Weissbach, S.H. Heinemann, L. Iverson, C.F. Wu, and T. Hoshi, High-quality life extension by the enzyme peptide methionine sulfoxide reductase. Proc Natl Acad Sci USA, 2002. 99(5): 2748-53