姓名：王雁

职称：教授、主任医师

一、教育经历

二、工作经历

三、研究方向（包括承担课题项目）

研究方向：眼科学、视觉光学、视光学、屈光手术

承担的主要课题：

1.国家自然科学基金（面上），批准号：81873684，名称：《基于AI技术探究多源临床表征对角膜屈光手术的精准量化及视觉优化机制的研究》，起止年月：2019.01-2022.12。获资助金额：57万元。项目状态：在研。主持。

2.国家自然科学基金（面上），批准号：81670884，名称：《基于角膜生物力学与形变精准量化的个性化眼模型对角膜屈光手术后视觉光学变化机制的研究》，起止年月：2017.01-2020.12。获资助金额：51万元。项目状态：在研。主持。

3.国家自然科学基金（面上），批准号：81470658，名称：《利用个性化大视场光学眼模型对角膜屈光术后视觉不良症状机制的研究》，起止年月：2015.01-2018.12。获资助金额：65万元。项目状态：在研。主持。

4.国家自然科学基金（面上），批准号：81170873，名称：《利用个性化眼模型研究角膜屈光术后色差与视觉不良症状的关联机制》，起止年月：2012.01-2015.12。获资助金额：60万元。项目状态：完成。主持。

四、学术兼职

四、近五年发表的学术论文

1.Li L, Schallhorn JM, Ma J, et al. Energy Setting and Visual Outcomes in SMILE: A Retrospective Cohort Study. Journal of Refractive Surgery, 2018, 34(1):11-16.

2.Ma J, Wang Y, Wei P, et al. Biomechanics and structure of the cornea: implications and association with corneal disorders. Survey of Ophthalmology, 2018, 1(1):15.

3.Hou J, Wang Y, et al. Comparison of effective optical zone after small-incision lenticule extraction and femtosecond laser–assisted laser in situ keratomileusis for myopia. JCRS. 2018

4.Zhang Y, Wang Y, Li L, et al. Corneal Stiffness and its Relationship With Other Corneal Biomechanical and Nonbiomechanical Parameters in Myopic Eyes of Chinese Patients. Cornea, 2018:1.

5.Ma R, Liu Y, Zhang L, et al. Distribution and Trends in Corneal Thickness Parameters in a Large Population-Based Multicenter Study of Young Chinese Adults. Investigative Ophthalmology & Visual Science, 2018, 59(8):3366.

6.Jiang Y, Wang Y, Zhang J, et al. Dynamic changes in higher-order aberrations after correction of lower-order aberrations with adaptive optics in myopic and emmetropic eyes. Applied Optics, 2018, 57(3):514.

7.Ma J, Wang Y, et al. Possible Risk Factors and Clinical Outcomes of Black Areas in Small-Incision Lenticule Extraction. Cornea.2018.

8.Wang M, Zhang Y, Wang Y, et al. Predicting Refractive Outcome of Small Incision Lenticule Extraction for Myopia Using Corneal Properties. TVST, 2018.

9.Xue C, Wang Y, et al. Preliminary Investigation of the Mechanical Anisotropy of the Normal Human Corneal Stroma. JO, 2018.

10.Cheng W, Liu L, Wang Y, et al. Real-time intraocular pressure measurements in the vitreous chamber of rabbit eyes during small incision lenticule extraction (SMILE). Current Eye Research, 2018.

11.Xiang Y, Shen M, Xue C, et al. Tensile biomechanical properties and constitutive parameters of human corneal stroma extracted by SMILE procedure. Journal of the Mechanical Behavior of Biomedical Materials, 2018, 85:102.

12.Chan T, Wang Y, Ng A, et al. Vector analysis of high (≥3 diopters) astigmatism correction using small-incision lenticule extraction and laser in situ keratomileusis. Journal of Cataract & Refractive Surgery, 2018. 231.Zhang L, Wang Y, Zhao W, et al. Corneal remodeling and spatial profiles following small incision lenticule extraction[J]. International Ophthalmology, 2018:1-10.

13.Zhang H, Wang Y, Li H. Corneal Spherical Aberration and Corneal Asphericity after Small Incision Lenticule Extraction and Femtosecond Laser-Assisted LASIK[J]. Journal of Ophthalmology, 2017(9):4921090.

14.Chen X, Wang Y, Zhang J, et al. Comparison of ocular higher-order aberrations after SMILE and Wavefront-guided Femtosecond LASIK for myopia[J]. Bmc Ophthalmology, 2017, 17(1):42.

15.Wang Y, Ma J, Zhang J, et al. Incidence and management of intraoperative complications during small-incision lenticule extraction in 3004 cases[J]. Journal of Cataract & Refractive Surgery, 2017, 43(6):796.

16.Li L, Cheng GPM, Ng ALK, Chan TCY, Jhanji V, Wang Y. Influence of Refractive Status on the Higher-Order Aberration Pattern After Small Incision Lenticule Extraction Surgery[J]. Cornea, 2017, 36.

17.Ma J, Wang Y, Li L, et al. Corneal thickness, residual stromal thickness, and its effect on opaque bubble layer in small-incision lenticule extraction[J]. International Ophthalmology, 2017:1-8.

18.Zhang H, Wang Y. Dry eye evaluation and correlation analysis between tear film stability and corneal surface regularity after small incision lenticule extraction[J]. International Ophthalmology, 2017:1-6.

19.Wei P, Wang Y, Chan TCY, Ng ALK, Cheng GPM, Jhanji V. Determining total corneal power after small-incision lenticule extraction in myopic eyes. J Cataract Refract Surg. 2017 Nov;43(11):1450-1457.

20.Wu Y, Wang Y. Detailed Distribution of Corneal Epithelial Thickness and Correlated Characteristics Measured with SD-OCT in Myopic Eyes[J]. Journal of Ophthalmology, 2017, 2017(6):1-8.

21.Chan TC, Cheng GP, Jhanji V, Wang Y. Adjuvant collagen crosslinking for treatment of epithelial ingrowth after small-incision lenticule extraction[J]. Clin Exp Ophthalmol. 2017 Oct 30.

22.Chan TCY, Ng ALK, Cheng GPM, Woo VCP, Zhang J, Wang Y, Jhanji V. Effect of the Learning Curve on Visual and Refractive Outcomes of Small-Incision Lenticule Extraction[J]. Cornea, 2017.

23.Li L, Schallhorn JM, Ma J, Zhang L, Dou R, Wang Y. Risk Factors for Opaque Bubble Layer in Small Incision Lenticule Extraction (SMILE)[J]. Journal of Refractive Surgery, 2017, 33(11):759-764.

24.Wenjing Wu，Yan Wang. Corneal high order aberrations of the anterior surface,posterior surface and total cornea after SMILE,FS-LASIK and FLEX surgeries. Eyes &Contact Lens,2016.

25.Shengsheng Wei, Yan Wang.The ultrastructural changes and cornea wound healing after SMILE and PRK procedures. Current Eye Research,2016.

26.Zhang JM, Wang Y, Wu WJ, Xu LL, Li XJ, Dou R. Vector analysis of low to moderate astigmatism with small incision lenticule extraction (SMILE): results of a 1-year follow-up. BMC Ophthalmology. 2015,15:8.

27.Wu D, Chen WQ, Li R, Wang Y. Efficacy and safety of topical diquafosol ophthalmic solution for treatment of dry eye: a systematic review of randomized clinical trials. Cornea. 2015 Jun;34(6):644-50

28.Zhang H, Wang Y, Xie S, Wu D, Wu W, Xu L. Short-term and long-term effects of small incision lenticule extraction (SMILE) on corneal endothelial cells. Cont Lens Anterior Eye. 2015,38(5):334-8.

29.Li X, Wang Y, Dou R. Aberration compensation between anterior and posterior corneal surfaces after Small incision lenticule extraction and Femtosecond laser-assisted laser in-situ keratomileusis[J]. Ophthalmic Physiol Opt,2015,35:540-51.

30.Dou R, Wang Y, Xu L, et al. Comparison of Corneal Biomechanical Characteristics After Surface Ablation Refractive Surgery and Novel Lamellar Refractive Surgery. Cornea. 2015;34:1441–1446.

31.Wenjing Wu, Yan Wang. The Correlation analysis between corneal biomechanical properties and the surgically induced corneal high-order aberrations after small incision lenticule extraction and femtosecond laser in situ keratomileusis. J Ophthalmol,2015:758196.

32.Wenjing Wu,Yan Wang , Lulu Xu. Epipolis-laser in situ keratomileusis versus photorefractivekeratectomy for the correction of myopia: a meta-analysis. Int Ophthalmol. 2015 Oct;35(5):757-63.

33.Lou Q, Wang Y, Wang Z, Liu Y, Zhang L, Fang H. Statistical characteristics of aberrations of human eyes after small incision lenticule extraction surgery and analysis of visual performance with individual eye model. Appl Opt. 2015,54(25):7490-3.

34.Lou Q, Wang Y, Wang Z, Liu Y, Zhang L, Zhai Y, Fang H. Investigation of aberration characteristics of eyes at a peripheral visual field by individual eye model. Appl Opt. 2015,54(19):5917-23.

35.Xu L,Wang Y, Li J,et al. Comparison of Forward Light Scatter Changes Between SMILE, Femtosecond Laser-assisted LASIK, and Epipolis LASIK: Results of a 1-Year Prospective Study. J Refract Surg,2015,31:752-758.

36.Zhang J,Wang Y,Chen X.Comparison of Moderate-to High Corrections Using WaveFront-Guided Laser In Situ Keratomileusis and Small-incision Lenticule Extraction. Cornea. 2016 Apr;35(4):523-30.

37.Wu Z,Wang Y,Zhang J,Chan TC,Ng AL,Cheng GP,Jhanji V. Comparison of corneal biomechanics after microincision lenticule extraction and small incision lenticule extraction.Br J Ophthalmol.2016 Aug,0:1-5.

38.Li H, Wang Y, Dou R, Wei P, Zhang J, Zhao W, Li L. Intraocular Pressure Changes and Relationship With Corneal Biomechanics After SMILE and FS-LASIK. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4180-4186.

39.Liu Y, Wang Z, Wang Y. A new method to accurately assess post-laser-surgery refractive changes with the intrinsic corneal power changes. Biome Mater Eng. 2015;26 Suppl 1:S825-32.

40.Wei Wang, Zhaoqi Wang,Yan Wang, Tong Zuo. Effects of the Cornea and the Crystalline Lens on the Aberrations of the Complete Eye. Princeton Univ Press. 2012, 6018(1):113-118

41.Yi Zhai,Zhaoqi,Wang Y,Yongji Liu.Optical design of head-mounted projective display for vein imaging.Electronics,Computer and Applications,IEEE.2014: 791-795.

42.Jin Y, Wang Y, Xu L, Zuo T, Li H, Dou R, Zhang J. Comparison of the Optical Quality between Small Incision Lenticule Extraction and Femtosecond Laser LASIK. J Ophthalmol. 2016;2016:2507973.

43.Wu W, Wang Y, Zhang H, Zhang J, Li H, Dou R. One-year visual outcome of small incision lenticule extraction (SMILE) surgery in high myopic eyes: retrospective cohort study. BMJ Open. 2016 Sep 21;6(9):e010993.

44.Hou J, Wang Y, Lei Y, Zheng X, Zhang Y. Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia. J Ophthalmol. 2016;2016:8582362.）

45.Wenjing Wu,Yan Wang, Lulu Xu. Meta-analysis of Pentacam vs.ultrasound pachymetry in central corneal thickness measurement in normal ,post-LASIK or PRK, and keratoconic or keratoconus-suspect eyes. Graefes Arch Clin Exp Opthamol. 2014 Jan;252(1):91-99.

46.Zhang L, Wang Y, Yang X. Ablation depth and its effects on corneal biomechanical changes in laser in situ keratomileusis and epipolis laser in situ keratomileusis. Int Ophthalmol. 2014 April;34(2): 157-164.

47.Di Wu, Yan Wang, Lin Zhang, Shengsheng Wei, Xin Tang. Corneal Biomechanical Effects of Small Incision Lenticule Extraction (ReLEx smile) Compared with Femtosecond Laser LASIK: A Prospective Study. J Cataract Refract Surg.2014 June;40(6): 954–962.

48.Yi Zhai, Yan Wang, Zhaoqi Wang, Yongji Liu, Lin Zhang, Yuanqing He and Shengjiang Chang, “Construction of special eye models for investigation of chromatic and higher-order aberrations of eyes”, Bio-Medical Materials and Engineering, 2014, 24(6): 3073~3081.

49.Yi Zhai, Yan Wang, Zhaoqi Wang, Yongji Liu, Lin Zhang, Yuanqing He and Shengjiang Chang, “Design of eye models used in quantitative analysis of interaction between chromatic and higher-order aberrations of eye”, Optics Communications, 2014, 332(1): 89~95.

六、荣誉和奖励

1.2018 天津市杰出人才

2.2018 首届海河医学学者

3.2017 中国女医师协会五洲女子科技奖

4.2016 中国眼视光年度贡献奖

5.2015 亚太眼科学会杰出贡献奖

6.2014 中华医学会奖

7.2014 天津市科学技术进步奖一等奖

8.2010 全国优秀科技工作者

9.2010 天津优秀科技工作者

10.2008 天津市科技进步奖一等奖

11.2007 天津市科学技术成果奖

12.2006 全国五一劳动奖章

七、联系方式

1.通讯地址：天津市和平区甘肃路4号

2.电话：022-27305083

3. E-mail：wangyan7143@vip.sina.com