张伟，医学博士，教授、主任医师，博士生导师，天津市眼科医院党委副书记、院长，天津市眼科与视觉科学重点实验室主任，天津市青少年近视防控中心主任，南开大学视光科学研究院院长。

现任中华医学会眼科学分会斜视与小儿眼科学组组长、中国眼科医师协会斜视与小儿眼病专委会主委、国家儿童医学中心眼科专科联盟专家委员会组长、全国防盲技术指导组副组长、亚太斜视与小儿眼科学会（APSPOS）理事、国际斜视与小儿眼科理事会（IPOSC）创始成员.

牵头制定国家卫生行业标准/共识5项，开创多项斜视手术新技术，斜视手术总例数2万余例居世界前列。主持国家自然科学基金等各级课题10余项，

       以第一/通讯作者在JAMA子刊,IOVS，BJO等发表学术论文百余篇。主编国家卫健委规划教材《斜视弱视与双眼视觉学》等2部，主编《中华眼科学》（第四版）斜视与小儿眼科学分卷，主编专著2部。获天津市科技进步一等奖、中国妇幼健康科技二等奖。获批国家发明专利等7项。任6本中英文学术期刊编委。

承担项目：

1. 人工智能驱动多源遥感时空建模探究儿童近视相关空间暴露组作用机制82571262，国家自然科学基金面上项目，2026.01 -2029.12。

2. 儿童青少年弱视筛查规范国家疾病预防控制局JK20240506，2024.10-2025.10。

3. 多模态影像联合组织力学实现斜视在手术精准量效评估的检查技术研究天津市科技计划项目（重点项目）22JCZDJC00160，2022.10-2025.09。

4. 婴幼儿智能视觉发育评估系统(iVAS)的研发 天津市教委科研计划项目（重点项目）2023YXZD03，2023.12-2026.1。

5. 基于OCT-眼底图像多模态影像的孤独症谱系障碍自动诊断方法研究 天津市计量科技项目 2024TJMT032，2024.05-2027.06。

6. ipRGCs-脑信号通路在近视发生发展中的作用机制研究 南开大学视光科学研究院项目 NKSGZ202302，2024.06-2027.06。

代表性学术论文

1.Niu R, Wang J, Pan X, Ran M, Hao P, Zhang W, Guo Y, Zhang W*. Curcumin inhibits ferroptosis-mediated vascular occlusion by regulating the CXCL10/CXCR3 axis in retinopathy of prematurity. Mol Med. 2025 Mar 24;31(1):113. doi: 10.1186/s10020-025-01161-1. PMID: 40128669.

2.Songwen Xu , Di Yang , Weike Wang , Wenguang Chen, Wei Zhang* , and Yanmei Liang*.Suppression of autocorrelation artifacts in PS-OCT images based on spectral phase interpolation.Applied Physics.Accepted.DOI: 10.1063/5.0245580

3.Niu R, Lv P, Hao R, Zhang W*. Comprehensive analysis of strabismus reoperations: clinical insights and progression factors. BMC Ophthalmol. 2024 Oct 11;24(1):446. doi: 10.1186/s12886-024-03712-2. PMID: 39394059; PMCID: PMC11468484.

4.Wang, X., Sun, Y., Luan, C., Yang, S., Wang, K., Zhang, X., Hao, R., Zhang, W*. Effect of hydrogen-rich saline on melanopsin after acute blue light-induced retinal damage in rats. PHOTOCHEM PHOTOBIOL. 2024; doi: 10.1111/php.13952

5.Guo, Y., Qin, J., Sun, R., Hao, P., Jiang, Z., Wang, Y., Gao, Z., Zhang, H., Xie, K., Zhang, W*, Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice. BIOL RES. 2024; 57 (1): 43. doi: 10.1186/s40659-024-00515-z

6.Wang, Z, Hu, Q, Tian, C, Wei Zhang* et al. Prophylactic Effects of n-Acethylcysteine on Inflammation-induced Depression-like Behaviors in Mice. NEUROSCIENCE. 2024; 549 42-54. doi: 10.1016/j.neuroscience.2024.05.005

7.Yang T, Li X, Wang K, Zhang Q, Hao R, Zhang W*. MRI evaluation of cranial nerve abnormalities and extraocular muscle fibrosis in duane retraction syndrome and congenital extraocular muscle fibrosis. Graefes Arch Clin Exp Ophthalmol. Published online March 26, 2024. doi:10.1007/s00417-024-06454-5

8.Ran, M, Yin, L, Guo, Y, Zhang, W*. Alterations in Adipocytokine Signaling Pathway and Pyroptosis in Neonatal Hypoxic-ischemic Encephalopathy. CURR MED CHEM. 2024-02-16; doi: 10.2174/0109298673293975240214091034. PMID: 38549539;

9.Tao J, Hao R, Guo Y, Zhang W*. Characteristics of Visual Function in Children With Cerebral Palsy and Intellectual Disabilities in Urban Beijing. Transl Vis Sci Technol. 2024;13(2):7. doi:10.1167/tvst.13.2.7

10.Chen F, Dong X, Wang Z, Wu T, Wei L, Li Y, Zhang K, Ma Z, Tian C, Li J, Zhao J, Zhang W*, Liu A, Shen H. Regulation of specific abnormal calcium signals in the hippocampal CA1 and primary cortex M1 alleviates the progression of temporal lobe epilepsy. Neural Regen Res. 2024 Feb;19(2):425-433. doi: 10.4103/1673-5374.379048. PMID: 37488907.

11.Li X, Li L, Qin W, Cao Q, Mu X, Liu T, Li Z, Zhang W*. Urban living environment and myopia in children. JAMA Netw Open. 2023;6(12):e2346999. doi:10.1001/jamanetworkopen.2023.46999

12.Wang X, Sun Y, Wang K, Yang S, Luan C, Wu B, Zhang W*, Hao R. Effects of blue light exposure on ocular parameters and choroidal blood perfusion in Guinea pig [published online ahead of print, 2023 Aug 24]. Exp Eye Res. 2023;235:109619. doi:10.1016/j.exer.2023.109619

13.Rui Hao,Yang Wang, Kailei Wang, Ang Wei, Wei Zhang*. A multimodal MRI study of functional and structural changes in concomitant exotropia. Experimental and Therapeutic Medicine. 2023 26: 442.DOI: 10.3892/etm.2023.12141

14.Yatu Guo, Quan Zhang, Tingting Zhang, Lingzhi Guo, Shichang Liu,, Kanxing Zhao, Wei Zhang*, Magnetic Resonance Imaging Findings in Patients With Duane Retraction Syndrome. Journal of Neuro-Ophthalmology 2023;00:1–6 doi: 10.1097/WNO.0000000000001909

15.Liao J, Li Y, Zhang W*. Binocular summation of visual acuity and contrast sensitivity in children with intermittent exotropia. BMC Ophthalmol. 2023 Jun 1;23(1):245. doi: 10.1186/s12886-023-02961-x. PMID: 37264304; PMCID: PMC10233972.

16.Liang B, Tang C, Zhang W*, Xu M, Wu T. N-Net: an UNet architecture with dual encoder for medical image segmentation. Signal Image Video Process. Published online March 22, 2023. doi:10.1007/s11760-023-02528-9

17.Liu Y, Meng D, Wang Y, Wang X, Xue C, Hao R, Zhang W*. Ocular biological parameters and prevalence of myopia in vocational high school and general high school in China. Front Public Health. 2023 Mar 20;11:1100437. doi: 10.3389/fpubh.2023.1100437. PMID: 37020816; PMCID: PMC10067628.

18.Chen L, Sun L, Xue C, Li S, Wang J, Shen X, Gao S, Zhou Z, Xu Y, Huang S, Li Z, Yang X, Guo Y, Zhang W*. Refractive errors and ocular findings in children and adolescents with mental disorders: a retrospective study. BMC Ophthalmol. 2023 Jan 3;23(1):4. doi: 10.1186/s12886-022-02704-4. PMID: 36597100; PMCID: PMC9808948.

19.Hao R, Wang Y, Chen L, Liu Y, Zhang W*. Differences in inferior oblique muscle satellite cell populations between primary and secondary inferior oblique muscle overaction [published online ahead of print, 2022 Oct 27]. Ophthalmic Res. 2022;10.1159/000527742. doi:10.1159/000527742

20.Gong Y, Wang X, Wang Y, Hao P, Wang H, Guo Y, Zhang W*. The effect of a chrysanthemum water extract in protecting the retina of mice from light damage. BMC Complement Med Ther. 2022 Aug 26;22(1):224. doi: 10.1186/s12906-022-03701-2.

21.Ding J, Chen L, Li Y, Zhao K, Zhang W*. Predicting Risk Factors for Consecutive Esotropia Failed with Conservative Therapy. Semin Ophthalmol. 2021 Feb 17;36(1-2):14-18. doi: 10.1080/08820538.2021.188426

22.Tengyue Zhang, Shiyong Xie, Ya ngchen Liu, Caihong Xue, Wei Zhang*.Effect of amblyopia treatment on macular microvasculature in children with anisometropic amblyopia using optical coherence tomographic angiography. Sci Rep. 2021 Jan 8;11(1):39.doi: 10.1038/s41598-020-79585-

23.Xiupeng Cao, Yatu Guo, Yuchuan Wang , Hao Wang, Dong Liu, Yibo Gong, Jue Wang, Xia Chen, Wei Zhang*. Effects of high-fat diet and Apoe deficiency on retinal structure and function in miceSci Rep. 2020 Nov2; 10(1):18601. doi:10.1038

24.Fang Xie, Xin Guo, Wei Zhang*.Single-stage superior oblique tendon recession with suture adjustment under topical anesthesia and sedation for A-pattern strabismus with superior oblique overaction[J]. JAAPOS. 2020 Aug ;24(4):219.e1-219.e7.doi: 10.1016/j.jaapos.2020.04.010.

25.YuePing Li, Yuchuan Wang, Wei Zhang*. A case of isolated amyloidosis in extraocular muscle mimicking thyroid eye disease. JAAPOS. 2020 Feb 20:S1091-8531(20)30030-6. doi: 10.1016/j.jaapos.2019.12.009.

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联系地址：天津市和平区甘肃路4号天津市眼科医院