姓名：李轩

职称：主任医师、研究员

一、教育经历

1.2006年日本福井大学博士研究生毕业

2.1996年中国医科大学硕士研究生毕业

3.1990年中国医科大学临床医学专业毕业

二、工作经历

（写主要工作经历）

现任南开大学附属眼科医院主任医师、研究员

曾于美国康奈尔大学、匹兹堡大学、日本福井大学博士后、学术研究员

三、研究方向（包括承担课题项目）

以角膜-眼表疾病为主的眼前节疾病

国家自然科学基金、天津市自然科学基金以及国家人社部留学人员科技活动优秀类项目等课题

目前在研课题：MicroRNA-29在角膜基质混浊形成中的作用与分子机制，课题来源：天津市既然科学基金，项目编号：20JCYBJC01450，经费额20万元。

四、学术兼职

中华医学会眼科学分会眼免疫学组委员

中国医师协会眼科学分会葡萄膜炎与免疫专业学组委员

五、近五年发表的学术论文

1.Chen Guo,Jinghua Liu, Peng Hao,Yuchuan Wang,Shuangshuang Sui,LinghanLi, Ming Ying,Ruifang Han, Liming Wang,Xuan Li*.Thepotential inhibitory effects of miR-19b on ocular inflammationupstream of JAK/STAT pathway in a murine model of allergicconjunctivitis.InvestOphthalmol Vis Sci.2020Mar 9;61(3):8.

2. Yongyingzhou, Ting Wang,Yuchuan Wang, Fan-Lan Meng, Ming Ying,Ruifang Han, Peng Hao, LimingWang, XuanLi*.Blockade of extracellular high-mobility group box 1 attenuatesinflammationmediated damage and hazegrade in mice with cornealwounds. InternationalImmunopharmacology.2020Volume 83, 106468

3. Xiaohanzhang, XuanLi*.Effectof rigid gas permeable contact lens on keratoconus progression: areview.  IntJ Ophthalmol.2020, 13(7): 1124-1131.

4. Jinghua Liu#, Ying Liu#,Liming Wang, Xiaohan Zhang, Peng Hao, XuanLi*.Progressivehemifacial atrophy with characteristic ocular manifestations in aChinese patient with a CRB1 mutation.Journalof International Medical Research.2020, 48(5): 300060520910635.

5.Ruifang Han,Peng Hao, Liming Wang, Jun Li, Shuangshuang Sui, Yuchuan Wang, MingYing, Jinghua Liu, Xin Tang, XuanLi^*.MicroRNA-34a inhibits epithelial-mesenchymal transition of lensepithelial cells by targeting Notch1.ExperimentalEye Research.2019,185: 0-UNSP 107684.

6.Jinghua Liu, Linhan Li,Xuan Li*.Effectiveness of CryopreservedAmniotic Membrane Transplantation inCorneal Ulceration: A Meta-Analysis. Cornea.2019, 38(4): 454-462.

7.Xu Liang, Yue Zhang, Yu-Peng Li, Wan-Rong Huang, Jia-Xing Wang,XuanLi*.Frequency and Risk Factors for Neovascular Glaucoma AfterVitrectomyin Eyes with Diabetic Retinopathy: An Observational Study.Diabetestherapy.2019, 10(5): 1801-1809.

8.Xi Chen, Ruifang Han, Peng Hao, Liming Wang, Meixin Liu, MeihuaJin,Dexin Kong, XuanLi*.Nepetin inhibits IL-1β induced inflammationvia NF-κB and MAPKssignaling pathways in ARPE-19 cells.Biomedicine&Pharmacotherapy.2018,101: 87-93.

9.Guangjie Liu, Peng Hao, Jie Xu, Liming Wang, Yuchuan Wang, RuifangHan, Ming Ying, Shuangshuang Sui, Jinghua Liu, XuanLi*.Upregulation ofmicroRNA-17-5p contributes to hypoxia-inducedproliferation in humanpulmonary artery smooth muscle cells throughmodulation of p21 and PTEN.RespirRes.2018.10, 19(1).

10. Yuchuan Wang, Yuan Tian,Jingyong Lin, Luxia Chen, Liming Wang, Peng Hao, Ruifang Han, MingYing, XuanLi*.XinTang; Assessment of p16 expression and HPV infection in adenoidcystic carcinoma of the lacrimal gland.MolecularVision.2018,24: 143-152.

11.Zhixin Jiang, Guangjie Liu, FanlanMeng, Weiyi Wang, Peng Hao,YangXiang, Yuchuan Wang, Ruifang Han, Fang Li, Liming Wang, XuanLi*.Paracrineeffects of mesenchymal stem cells on the activation ofkeratocytes.The Britishjournal of ophthalmology.2017, 101(11):1583-1590.

12.Fang Li#, Peng Hao#, Guangjie Liu, Weiyi Wang, Ruifang Han,ZhixinJiang, XuanLi*.Effectsof 4-methylumbelliferone and high molecularweight hyaluronic acid onthe inflammation of corneal stromal cellsinduced by LPS.Graefe'sarchive for clinical and experimentalophthalmology.2017, 255(3): 559-566.

13.Yuchuan Wang, Jinyong Lin, Luxia Chen, Liming Wang, Peng Hao,RuifangHan, Ming Ying, XuanLi*. Expressionof Peroxiredoxin 2 andVascular Endothelial Growth Factor Receptor 2in Pterygium.Cornea.2017,36(7): 841-844.

14. Fang Li,Zhi-Xin Jiang,Pen Hao,Xuan Li*. AMeta-analysis of Central Corneal Thickness Changes With OvernightOrthokeratology.Eyeand Contact Lens: Science and Clinical Practice.2016, 42(2): 141-146.

15. Lu Tian,YatuGuo, MingYing, Yang-chen Liu,XuanLi*, YanWang*.Co-existence of myopia and amblyopia in a guinea pig model withmonocularform deprivation, Annals of Translational Medicine, 2021,9(2): 110.

六、荣誉和奖励

七、联系方式

天津市和平区甘肃路4号

27313336-83002

yatrans@163.com