李春君-硕士研究生导师






    


姓名:李春君

职称:主任医师、教授

导师类型:硕士研究生导师

 

一、教育经历

1.1995/09-2000/06,山东医科大学,临床医学,学士

2.2004.09-2007/06,天津医科大学,内分泌与代谢病,硕士

3.2010/09-2013/06,天津医科大学,内分泌与代谢病,博士

二、工作经历

2000/07-2002/07,天津医科大学总医院,大内科,规范化培训,住院医生

2002/08-2013/12,天津医科大学代谢病医院,内分泌科,住院医师/主治医师

2010/01-2012/01,美国天普大学,内分泌科,访问学者

2013/12-2017/12,天津医科大学代谢病医院,内分泌科,副主任医师

2016/12-至今,天津医科大学,副教授

2017/01-至今,天津医科大学,基础医学院,博士后

2017/12-2019/06,天津医科大学代谢病医院,内分泌科,主任医师

2019/06-至今,天津市人民医院,内分泌科/健康管理中心,主任医师

三、研究方向(包括承担课题项目)

1. 天津市卫生健康科技项目面上项目,TJWJ2022MS019, 2022.07.012025.06.30, 10万元,细胞外小囊泡在2型糖尿病缓解中的作用研究,在研,第二参加人

2. 天津市自然科学基金重点项目,19JCZDJC36100,内脏脂肪源性外泌体携带的 miRNAs 调节肝脏脂质代谢的机制研究,2019-042022-0320万元,已结题,主持

3. 国家自然科学基金面上项目,81870547Axin1Tiam1在运动/肌肉收缩促进骨骼肌摄取葡萄糖和改善胰岛素抵抗机制中作用研究,2019/01-2022/1257万,已结题,第二参加人

4. 天津市教委自然科学基金一般项目,2018KJ047SDF1α过表达的MSC调控胰腺导管细胞β细胞转化的机制研究,2019/01-2021/126万,已结题,第二参加人

5. 天津市自然科学基金重点项目,18JCZDJC35500FGF2α抑制非增殖性糖尿病视网膜病变中视网膜周细胞凋亡的机制研究,20万,2018/04-2021/03,已结题,第二参加人

6. 白求恩-默克糖尿病研究基金,G2016014,羟苯磺酸钙改善微量白蛋白尿和尿中足细胞自噬相关miRNAs的研究,2017/01-2019/1220万,已结题,主持。

7. 国家青年自然科学基金项目,81300663,巨噬细胞源性MVs促进2型糖尿病动脉粥样斑块薄壁纤维帽形成的机制研究,2013/01-2016/12,23,已结题,主持。

四、学术兼职

中华医学会糖尿病学分会青年委员

中华医学会全科学会委员

天津市医学会糖尿病学分会委员

天津市医学会内分泌学分会委员

五、近五年发表的学术论文

1. Zhang S, Huang Y, Li J, Wang X, Wang X, Zhang M, Zhang Y, Du M, Lin J, Li C. Increased visceral fat area to skeletal muscle mass ratio is positively associated with the risk of cardiometabolic diseases in a Chinese natural population: A cross-sectional study. Diabetes Metab Res Rev. 2023 Feb;39(2):e3597.(IF:8.128)

2.Xiao-HeWang, Wei-Ran Jiang, Min-Ying Zhang, Ying-Xin Shi, Yun-Ping Ji,Chun-Jun Li1# and Jing-Na Lin#.The visceral fat area to leg muscle massratiois significantly associated with the riskofhyperuricemia among women: a crosssectional study.Biologyof Sex Differences,2021,12(1):17.(IF:3.267)

3.Ying-XinShi, Xiang-Yu ChenHui-NaQiu, Wei-Ran Jiang, Min-Ying Zhang, Ya-Ping Huang,Yun-Ping Ji, ShiZhang, Chun-Jun Li #and Jing-Na Lin#.Visceralfat area to appendicular muscle mass ratio as a predictor fornonalcoholicfatty liver disease independent of obesityScndinavianJournalofGastroenterology,2021,56(3):312–320.(IF: 2.13)

4.Chun-JunLi*, Qian-Hua Fang*, Ming-Lin Liu, Jing-Na LinCurrent understanding on the role of adipose-derived extracellular vesiclesinmetabolic homeostasis and diseases: Communication from distancebetween cells/tissuesTheranostics,2020, 10(16):7422-7435. (IF: 8.063)

5.WangX-H, Lin J-N, Liu G-Z, Fan H-M, Huang Y-P, Li CJ# and Yan HY# .WomenAre at a Higher Risk of Chronic Metabolic Diseases Compared to MenWith Increasing Body Mass Index in China. Front. Endocrinol. 11:127.doi: 10.3389/fendo.2020.00127.Published online 2020March12.IF:3.634

6.FangQH, Shen QL, Li JJ, Yang Y, Guo JJ, Cheng Y, Zhou HC, Niu WY, ChenLM, Li CJ#, Sun B#. Inhibition of microRNA-124a attenuatesnon-alcoholic fatty liver disease through upregulation of adiposetriglyceride lipase and the effect of liraglutide intervention.Hepatol Res. 2019 Jul;49(7):743-757. IF:3.44

7.YueWang, Yun-hong Lu, Chao Tang, Mei Xue, Xiao-yu Li, Yun-peng Chang,Ying Cheng, Ting Li, Xiao-chen Yu, Bei Sun, Chun-jun Li#, Li-mingChen#. Calcium Dobesilate Restores Autophagy by Inhibiting theVEGF/PI3K/AKT/mTOR Signaling Pathway. Front Pharmacol. 2019; 10: 886.Published online 2019 Aug 9. (IF:3.845)

8.DingMin, Fang Qian-Hua, Cui Yuan-Tao, Shen Qi-Ling, Liu Qian, WangPeng-Hua,Yu De-Min, Li Chun-Jun#. Liraglutide prevents β-cellapoptosis via inactivation of NOX2 and its related signaling pathway.J Diabetes Complications.2019 Apr01IF:2.684

9.MinDing, Jianying Shi, Yunzhi Xing, Bei Sun, Qianhua Fang, JingyunZhang, Qiumei Zhang, Liming Chen, Demin Yu, Chunjun Li#. Serumadipocyte fatty aci-binding protein levels are associated withperipheral arterial disease in women, but not men, with type 2diabetes mellitus. Journal of Diabetes. 2018;10(6):478-486. (IF3.213)

10.YunpengChang, Bei Sun, Zhe Han, Fei Han, Shaolan Hu, Xiaoyu Li, Mei Xue,Yang Yang, Li Chen, Chunjun Li#, Liming Chen#. Saxagliptin attenuatesalbuminuria by inhibiting podocyte epithelial-to-mesenchymaltransition via SDF-1αin diabetic nephropathy. Front Pharmacol.2017;8:780. (IF 3.813)

11.ChunjunLi*, Bei Sun, Qian HuaFang, Min Ding, Yun Zhi Xing, Li MingChen,DeMin Yu. Saxagliptin induces β-cell proliferation throughincreasing stromal cell-derived factor-α in vivo and in vitro. FrontEndocrinol(Lausanne). 2017;8:326. (IF 3.519)

12.JinjinLi, Xiaojuan Liu, Qianhua Fang, Min Ding and Chunjun Li#. Liraglutideattenuates atherosclerosis via inhibiting ER induced macrophagederived microvesicles production in T2DM rats. Diabetology&MetabolicSyndrome.2017; 9:94. (IF:2.413)

13.LiJun Duan, Min Ding, LiJunHou, YuanTao Cui, ChunJun Li#, De Min Yu#.Long noncoding RNA TUG1 alleviates extracellular mareix accumulationvia mediating microRNA-377 targeting of PPARγ in diabeticnephropathy. BiochemBiophys Res Commun. 2017 Sep;484(3):598-604.(IF:2.559)

14.DingM, Liu L, Zhang L, ChunJun Li#. Changes in insulin resistance arerelated to liraglutide-induced HMW-Adiponectin increase in obese type2 diabetes. Int J Clin Exp Med 2017;10(7):10257-10266.(IF: 1.069)

六、荣誉和奖励

天津市特聘教授青年学者

天津市131”第一层次创新型人才

天津市首批青年医学新锐

七、联系方式

通讯地址:天津市红桥区芥园西道190号天津市人民医院健康管理中心和内分泌科

电话:022-27557667

E-maili_chunjun@126.com